The so-called fat fat Gewebshormon leptin, that can a key role in the control and potentially reverse diabetes, a role that has to do with his association with weight loss.
The hormone leptin has fat hormone synchronized after numerous studies have shown that it promotes weight loss, which in turn has a positive effect on the control of diabetes.
But a new study suggests that the small amounts of leptin - too small, are sufficient to promote weight, to the activity of a gene known as IGFBP2 in the liver, which improves diabetes in animals and have to control the same effect in humans.
"It was surprising to me as powerful leptin was the treatment of diabetes," said researcher Jeffrey Friedman of Rockefeller University in a press release. "It was very significant impact in plasma levels were undetectable."
Researchers confirm, that the positive effects of leptin on combating diabetes independent of the effects of the hormone weight loss. Previous studies have shown that leptin hormone therapy corrected high blood glucose and insulin levels in mice and humans with low hormone.
To examine the effects of leptin on the control of diabetes, researchers first identified the lowest dose of leptin that improved resistance to insulin and diabetes without animals eat less or lose weight.
It then examined the effects of this low doses of leptin on the activity of genes in the liver of animals.
The results published in the metabolism, leptin IGFBP2 showed increased mice cell see obesity and diabetes and has reversed her diabetes. Researchers who also found mice with fat hormone treated responded to insulin, three times better than untreated mice.
Need to continue their studies to determine whether the treatment of leptin in people has the same positive effect on the control of diabetes.