US researchers found that grenades with six natural, may prevent the links the growth of hormone-dependent breast cancer by blocking the enzyme aromatase, which changes of androgens, estrogens. But experts caution, doesn't mean that people expect that the same results grenades, food, because it is a study of "in vitro" (test tube) and the results on the lab bench reflected always in animals and humans.
The study, published in the issue of 1 January of cancer prevention research, is the work of Dr. Shiuan Chen, Director of the Department of biology cell tumor in the city of hope Beckman Research Institute, Duarte, California and colleagues in the city of hope and the Center for human nutrition at the school of medicine, David GeffenUniversité of California, Los Angeles.
The study projected she Explorer 10 connections in a group called Ellagitannins.
Chen and his team have found that the connection was with the greatest influence of Urolithin B (UB), the production of several mechanisms of estrogen to inhibit that fuel the growth of breast cancer.
She also found that UB grow estrogen sensitive cancer cells prevents.
Chen said the press, that:
"By eliminating the production of estrogen, the hormone-sensitive breast tumors cancer can prevent Urolithin b and other phytochemicals in grenades."
Other secondary plant substances, which they were found, methyliert Urolithin A (AU), UA-methyl sulfate, ACETYLIERTE UB UB and UB: they also inhibit the activity of aromatase, but to a lesser extent.
Other studies have found that Pomegranate juice is rich in antioxidants and contains connections that can control the growth of breasts and human prostate cancer, researchers said.
Chen said that the results of the study show that:
"Grenada recording can be a viable strategy for the prevention of breast cancer."
According to a report by cancer research UK, Chen explains that he and his team explain results were surprised that she had found previously other fruits such as grapes, could also aromatase, inhibit "but different connections phytochemicals in pomegranate and grapes", he said.
Experts warn that studies are needed before we can be sure that UB effective against human hormone-dependent breast cancer: women should not begin intensive grenades as a result of the study.
It is an in-vitro study (test tube), and sometimes, these findings translate into human and animal studies: for example it is essential, that these substances are not well absorbed in the body are by eating only grenades.
Dr. Laura Bell, officer of scientific information, the Cancer Research UK, reported the press, the:
"It is too large, a jump to the conclusion of this research from early stage, which eat grenades can to prevent that the study with large amounts of chemical products was conducted purified cells cultured in the laboratory of hormone-dependent breast cancer.".
"Cancer screening, most foods contain many natural chemicals and we need to understand the combined effect of this, when the think contracts in the body as, where appropriate, a certain food your chance of developing cancer, affect can", she explained, adding that many large studies that have shown:
"By eating healthy, balanced diet rich in fiber, fruits and vegetables and little processed and you can help red meat, saturated fat and salt, to reduce the risk of several types of cancer."
Drugs, such as such as anastrozole (Arimidex AstraZeneca) to block breast cancer also the action of aromatase.
Source: "grenade Antiproliferative exhibition of compounds, which from Ellagitannins and Antiaromatase activity in the cell in vitro."
Lynn S. Adams, Yanjun Zhang, Navindra, Seeram s., David Heber and Shiuan Chen.
Research on cancer prevention 3: 108-113, 3, 1 January 2010