Pharmaceutical company GlaxoSmithKline published a detailed the new report that potentially make suicide more likely people with depression might its antidepressant paxil.
But in clinical trials, the company found that suicide rates were relatively low - for those, the paxil placebo use 0.34% vs. 0.05% for the taking of the pill.
The report also shows that the results could not exclude that the difference by chance.
"The scientific evidence justifies, that paroxetine, not" the active ingredient in Paxil, "Causes thinking suicide, attempted suicide, self-harm or suicide," Sarah Alspach, a spokesman for the drug companies, told Reuters Health via e-Mail.
"" However, all patients should be started on treatment with antidepressants be monitored appropriately and observed closely for worsening clinic, suicidality, or unusual changes in behavior,", said Alspach."
The link between the antidepressants and suicide has a very sensitive issue for regulators and manufacturers of drugs for some time. Current data were published on the website of GlaxoSmithKline in response to growing concerns in 2006.
The food and Drug Administration (FDA) has a warning issued, in 2004, that minors, the use of Antidepressants can have an increased risk of suicidal tendencies. The Agency found that 4% of the children, has the use of antidepressants in clinical trials about, thought about suicide, self mutilation, or indeed tried to commit suicide.
The FDA, that, in comparison to only 2% of children with a placebo or had this idea or attempt suicide.
The FDA expanded its warnings in 2006 on young adults up to the age of 25. All antidepressants are required to carry a label of "black box" warning against the possible risk of suicidal thoughts and behaviour in the use of drugs.
The study showed a less more clearly how antidepressants influence the thoughts and attitudes of adults.
GSK report was 57 paxil for a variety of psychiatric diseases, where about 15,000 patients used on the basis of clinical studies. The study found that overall the drug seemed show an increase in suicidal thoughts and behavior.
He however showed a difference from 18 to 24 - years. The authors have for this age group said, thought 2.58% of the users of paxil or attempt suicide, compared to 1.29 per cent of those who use the placebo treatment.
Yet again, these findings would be due after the random due to the low suicidal thoughts and behavior.
Data from 19 trials including only people with depression show that among the 3 455 paxil user suicide, 0.34% to 0.05% of the 1-978-people, who received the placebo tries.
Despite the amazing results, the report will be published in the journal of clinical Psychiatry, you will notice that paxil was effective in all to treat of the symptoms of mental illness.
"" Paxil has proven to be effective and has helped, many people struggle with mental illness a life more productive and happier to live,"Alspach told Reuters Health."
The center of Les centres for disease control and prevention (CDC), said that antidepressants among the most commonly prescribed class of drugs to the United States.